Each vessel hull creates its own unique wake-field. This master’s thesis covers optimization of propeller-hull interaction implementing Computational Fluid Dynamic (CFD) simulations. Furthermore, to reduce computational time, the propeller blade is divided into two-dimensional sections, which are coupled with one another. Boundary conditions for 2D hydrofoil shape optimization are established in the initial simulation of propeller-hull interaction. Hydrofoil optimization is performed in this two-dimensional space. Autonomous input of geometric modifications is provided by parametric modelling. The efficiency of the optimization is evaluated through integral quantities and performance characteristics. Moreover, advanced optimization algorithms coupled with an estimated wake-field can significantly enhance propeller efficiency. This efficiency improvement contributes to the sustainable development of the maritime industry by reducing fuel consumption and subsequent greenhouse gas emissions.